TLR4 and breast carcinoma: Related literature reports suggest that TLR 4 is a key molecule involved in breast cancer cell eradication or induction of breast cancer development and normal cell transformation, in normal breast tissue, TLR4 fights breast cancer cells by recognizing their DAMPs, but overexpression of TLR4 and changes in its signaling pathway are vital factors that alter the function of TLR4 against breast cancer and promote the development and metastasis of breast cancer (5).