AFP and hepatocellular carcinoma: Multivariable analysis revealed independent significant indices for ER in HCC as serum AFP level > 400 ng/mL (OR [95% CI] = 5.721 [1.585 - 20.649], P = 0.008), MVI (4.854 [1.404 - 16.782], P = 0.013) and Rad-score (3.352 [2.008 - 5.597], P < 0.001) (Table 4).