For example, one trial using community laboratory data from British Columbia reported a mean TTR of 55.4%.9 Another study investigating TTR for 150 patients with atrial fibrillation managed by a nurse-administered warfarin dosing protocol found a time-weighted TTR of 58.8%.8 The mean and time-weighted mean TTRs reported for the primary outcome in our study were nearly 20% higher than either of these results (74.2% and 76.3%, respectively). This evidence concerns the gene TTR and atrial fibrillation.