As per our centre’s donor standard evaluation protocol, every donor underwent extended hereditary thrombophilia testing including PS, PC, and AT-III activity, and levels of lupus anticoagulant, IgG anti-CL antibodies, IgM anti-CL antibodies, and anti-B2 GPI antibodies along with conventional coagulation parameters. The gene discussed is SERPINC1; the disease is Rare hereditary thrombophilia.