KLK3 and neoplasm: In our study, univariate analysis revealed that age, prostate volume, PSA, PSAD, PI-RADS score, total biopsy core length, total biopsy tumor length, and tumor percentage in biopsy cores were nonsignificant variables for GG upgrade, whereas the number of biopsy cores, number of positive biopsy cores, Gleason grade, and tumor size were found to be significant predictors of GG upgrade.