FGF2 and malignant pleural mesothelioma: Moreover, it has been reported that tumor-associated fibroblasts can boost the progression of malignant pleura mesothelioma through a cytokine network involving fibroblast growth factor-2 (FGF-2), platelet-derived growth factor-AA (PDGF-AA), and hepatocyte growth factor (HGF) [13].