As a popular research topic in recent years, Kcr has been associated with various pathophysiological processes and diseases, including embryonic development [58], neurodevelopment [56], neural differentiation [59], neuron flammation [60], AD [61], neonatal hypoxic-ischemic encephalopathy [62], acute kidney injury [44], HIV [63], and even depression [43]. The gene discussed is CLEC4F; the disease is Alzheimer disease.