For instance, transfection of miR-7 suppresses microglial NLRP3 inflammasome activation and decreased dopaminergic neuron degeneration by decreasing microglial activation in the PD model induced by MPTP (Titze-de-Almeida and Titze-de-Almeida 2018). The gene discussed is NLRP3; the disease is Parkinson disease.