miR-204 silencing suppressed mitochondrial autophagy by inhibiting Parkin, PINK1,,LC3II, and Beclin1 through STAT3 pathway and up-regulating TRPML1 expression in APP/PS1 transgenic AD mice and a cell model of AD induced by Aβ1-42 (Zhang et al. 2021a). This evidence concerns the gene PINK1 and Alzheimer disease.