STX2 and hemolytic-uremic syndrome: Previously studies have shown that STEC O157:H7 belonging to sub-lineage Ic harbouring stx2a with or without stx2c (for the most part corresponding with phage type (PT) 21/28) was the dominant type in the UK between 1995 and 2015 and remains a common cause of STEC-HUS in England3,6,8,9.