We found that SUMF1 expression was significantly correlated with glioma immune score, stromal score, ESTIMATE score, immune cells (aDC, B cells, CD8 T cells, cytotoxic cells, T cells, Tgd, Th17 cells, Th2 cells, and others), and immune cell markers (CD19, CD86, CD8B, CCL2, PDCD1, CD8A, CTLA4, CD79A, and others). Here, CCL2 is linked to central nervous system cancer.