LINC01116 promotes the proliferation, migration, and invasion of lung cancer, gastric cancer, and colorectal cancer cells.[17, 18, 19, 20] Although the role of LINC01116 in tumor cell proliferation and metastasis has been extensively studied, its role in the tumor immune microenvironment and metabolic reprogramming is still unknown. The gene discussed is LINC01116; the disease is lung cancer.