Our findings revealed an average ES incidence of 7.70%, with identified risk factors, including low thrombolysis in myocardial infarction (TIMI) flow grades (0–1), elevated cardiac troponin I (cTnI) levels, persistent hypotension, reperfusion arrhythmias, the right coronary artery being the infarct-related artery (IRA), increased diameter of the IRA, renal dysfunction, elevated creatine kinase-MB (CK-MB), and bradycardia. This evidence concerns the gene TNNI3 and myocardial infarction.