Targeting USP7 may weaken the interaction between PD‐1 and PD‐L1, sensitizing GC cells to T‐cell‐mediated killing and enhancing anti‐tumor immunity.[9] In Cancer‐associated fibroblasts (CAFs) within GC, USP7 deubiquitinates and stabilizes heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1), facilitating the packaging of miR‐522 into exosomes. Here, CD274 is linked to cancer.