Disease duration was shorter and there was a lower percentage of pancolitis, severe modified Mayo score, severe endoscopic Mayo subscore, and baseline corticosteroid use in the induction responder population compared with extended induction responder population; lower inflammatory markers (C-reactive protein, fecal calprotectin), prior biologic or tofacitinib failure, and lower overall percentage of failed biologics or tofacitinib were also observed (Supplementary Table 1). Here, CRP is linked to pancolitis.