Neutralization of TNF has also been recorded to have positive unintended consequences; patients with rheumatoid arthritis treated with anti‐TNF agents had a lower incidence of cardiovascular events and improved insulin resistance (Barnabe et al., 2011; Gonzalez‐Gay et al., 2006; Jacobsson et al., 2005; Kiortsis et al., 2005; van Eijk et al., 2009). The gene discussed is TNF; the disease is rheumatoid arthritis.