This dependency is not limited to MYC-driven tumor cells but also occurs in various other cancer cell lines, including lymphomas, prostate cancer, osteosarcoma, renal cell carcinoma, colorectal cancer, and small cell lung cancer [84, 86–90].These tumor cells rely on glutamine for cell survival and growth when MYC is activated. This evidence concerns the gene MYC and hereditary clear cell renal cell carcinoma.