Furthermore, the combination of the anti-CTLA-4 treatment with vaccination induced complete tumor regression in 3/5 mice (Fig. 6B-E), and PD-L1 blockade combined with the vaccination promoted tumor regression in 2/5 mice (Fig. 6B-E), compared to only 1/5 mice achieving tumor regression with CCL11-E6E7 immunization alone. The gene discussed is CTLA4; the disease is neoplasm.