In accordance we here show for the first time in SLE pregnancy that autoantibody positivity also separated into three clusters, the first dominated by positivity for anti-dsDNA/anti-Sm/anti-RNP/anti-chromatin, the second by anti-SSA/anti-SSB and the third by anti-CL/anti-β2GPI. Here, SSB is linked to systemic lupus erythematosus.