Together, those results indicated that the CXCL13-H group had significantly higher infiltration of multiple types of immune cells compared to the CXCL13-L group, which suggests that CXCL13-H is ‘hot’ tumor, whereas CXCL13-L is in a “cold” immune state (tumors with low immune infiltrate). The gene discussed is CXCL13; the disease is neoplasm.