In the same study, hepatic steatosis was more common in patients with ACTH-dependent Cushing’s syndrome than in those with ACTH-independent Cushing’s syndrome (27.6% vs. 18.2%, respectively), as well as in men than in women (33.2% vs. 26.0%, respectively) [60], although the latter difference was smaller than that observed in the previously mentioned Chinese study [68]. This evidence concerns the gene POMC and Cushing syndrome.