DNM1L and diabetes mellitus: The current work proposes Drp1 as a novel potential downstream effector of APG in the management of diabetes based on the following: first, Drp1 is a mitochondrial fission protein; upon its over-expression and/or over-activation, an imbalance in mitochondrial fission or fusion occurs, which becomes an evident driver in the pathogenesis of diabetes and its genitourinary drawbacks16,36,37.