Of these 11 SNPs, only one SNP (rs3094060), which colocalised with FLOT1 gene expression, showed a significant difference greater than 15% in allele frequency (AF) between the gnomAD general population (non-Finnish European), and the same type of CKD cases in both the NURTuRE-CKD and SKS datasets (Chi-square test with Yates’ correction P-value < 0.05; Supplementary Dataset 14)40. Here, FLOT1 is linked to chronic kidney disease.