The expression of USP39 in non-tumor samples (n = 23) was much lower than that in EC tumor samples (n = 552) (P < 0.05; Fig. 4A), and higher expression of USP39 was positively correlated with the clinical grade and FIGO stage of EC (P < 0.05; Fig. S5A, B). The gene discussed is USP39; the disease is neoplasm.