PTPRC and Testicular torsion: After testicular torsion, we found that the ratio of CD45+F4/80+ macrophages was significantly increased in the AAV8-shTRPM7-treated group compared to the control group (Supplementary Fig. 17c d), while the number of germ cells was markedly reduced on day 7 after testicular torsion (Supplementary Fig. 17e, f).