MYOC and glaucoma: Contributors to the GO term “negative regulation of cell adhesion” on the other hand included matrix metalloproteinases Mmp2 and Mmp14 which can remodel the extracellular matrix, Myoc (myocilin) which encodes a secreted protein linked to glaucoma [55] and Anxa1 (annexin A1), a mediator of glucocorticoid action [56].