XIST and psoriasis: KCNQ1OT1 acts as a molecular sponge for miR-145-5p and downregulate the expression of miR-145-5p.[29] NEAT1 promotes the onset of rheumatoid arthritis by regulating the miR-144-3p/ROCK2 axis.[30] The lncRNA XIST is highly expressed in psoriasis patients and is positively correlated with neutrophilic inflammation and psoriatic disease severity.