KCNQ1OT1 and myocardial infarction: The lncRNA NEAT1 inhibited the expression of ATG12 by suppressing the expression of mir-378a-3p, thus affecting the autophagy of cardiomyocytes.[25,45] A study validating qRT-PCR in 46 MI patients and 40 healthy controls showed a significant increase in KCNQ1OT1 expression in MI patients compared to that in control patients, which is consistent with our findings.[35] Moreover, in MI patients, KCNQ1OT1 expression was shown to be upregulated, while miR-26a-5p expression was downregulated.