GSTM1 and anemia (phenotype): β-thalassemia can be clinically categorized as β-thalassemia minor, intermedia, and major.[2] Patients with thalassemia intermedia present with mild-to-moderate anemia (Hb 7–10 g/dL) and do not require regular blood transfusions.[2,13] The proband in this case showed typical clinical manifestations of β-thalassemia intermedia.