ACVRL1 and neoplasm: The results showed increased production of proteins associated with signal transduction (tenascin R), transforming growth factor β signaling (follistatin-like 3 and activin A receptor type II-like 1), regulation of cell chemotaxis, apoptosis, and inflammatory responses (hepatocyte growth factor) in L. braziliensis-treated mice 35 days after tumor establishment (Figure 5J).