Sarcopenia was associated with significantly greater levels of BNP (MD: 87.76, 95% CI 20.74 – 154.78, I2 = 61%, P = 0.01) and NT-proBNP (MD: 947.45, 95% CI 98.97 – 1795.93, I2 = 35%, P = 0.03). The gene discussed is NPPB; the disease is sarcopenia.