MCL1 and mesothelioma: For example, IST-MES1 mesothelioma cell line treated with AZD5991 (MCL1 inhibitor) + AZ-3202 (BCL-Xli; also known as compound 15; ref. 17) had higher Bliss synergy excess for the window (0.823) versus matrix (0.180; Supplementary Fig. S1J).