ERBB2 and neoplasm: However, no significant associations were observed between HER2 positivity and gender (p = 0.345), age (p = 0.289), tumor size (p = 0.107), smoking status (p = 0.175), muscle invasion (p = 0.133), regional lymph node metastasis (p = 0.143) or primary site of the tumor (p = 0.066) as shown in Table 2.