Many microRNAs upregulated in PTSD. Also in PTSD groups, downregulation of miR-125a (as well as miR-181c); inhibitory effect of miR-125a on IFN-γ release in vitro. Interferon gamma (IFN-γ) and IL-17 were also found in the plasma. Significant increase of peripheral blood mononuclear cell numbers in PTSD patients vs. controls, which also correlated with anxiety. Supports immune dysregulation in PTSD. Here, IFNG is linked to post-traumatic stress disorder.