Moreover, data on the Arg1 and TGF-β1 (one of the main suppressors of immune cells) mRNA expression in peritoneal macrophages and in TAS cells of tumor-bearing mice, treated accordingly to Karanahan and Karanahan+GcMAF technologies, indicate that in peritoneal macrophages these treatments cause the elevated expression of arginase mRNA and have no effect on TGF-β1, while in TAS both factors are suppressed. Here, ARG1 is linked to neoplasm.