It also causes downregulation of Lymphoid enhancer‐binding factor‐1 (LEF‐1 gene) as well as decreases the xanthone (glucose) metabolism in tumor cells; all these actions result in a reduction of tumor volume (size) and decrease in tumor migration (movement to other cells) (Katti et al., 2018; Rodriguez‐Gonzalez et al., 2021; Tan et al., 2018). The gene discussed is LEF1; the disease is neoplasm.