TNF and Sepsis: Recently, a study shows that MAF significantly protects sepsis‐induced lung and kidney injuries by its anti‐inflammatory and antioxidant effects (Garrido et al., 2004; He et al., 2014; Zhang et al., 2020), which is associated with suppression of TNF‐α and nitric oxide (NO) production (Garrido et al., 2004), inhibition of NLRP3 inflammasome activation (Li, Xiong, et al., 2021), and upregulation of heme oxygenase‐1 (Gong et al., 2013).