BSCL2 and lipodystrophy: At least ten lipodystrophy-associated genes have been identified, including phosphate acetyltransferase (AGPAT2), phosphoinositide-dependent serine-threonine protein kinase (AKT2), seipin (BSCL2), caveolin 1 (CAV1) and perilipin 1 (PLIN1) (Kuivenhoven and Hegele, 2014).