Using Breast Cancer Gene-Expression Miner v5.0 (bc-GenExMiner v5.0), we conducted a meta-evaluation of clinical significance of FAM83D in BC and found that high expression levels of FAM83D are significantly associated with poor prognosis regarding to overall, disease-free, and distant metastasis-free survival (Fig. 6e-g). The gene discussed is SACK1D; the disease is breast cancer.