The region in chromosome 17 (band 17q21.32), where the SNP rs2316327 associated with general CHD and rs75230966 and associated with septal defects are located, contains several genes linked to heart development, CHD, and other cardiac phenotypes; MYL4, CDC27, GOSR2 and WNT9B [18, 26–28]. The gene discussed is CDC27; the disease is coronary artery disorder.