In order to shed light on the suggested relationships between GLP-1 analogs, ingestive behavior, and food preference, this review primarily focuses on studies which treated adults with obesity and/or type 2 diabetes with semaglutide and liraglutide, and which recorded measurements of appetitive behavior, consummatory behavior, and food preferences. The gene discussed is GCG; the disease is obesity due to melanocortin 4 receptor deficiency.