HLA-DRB1 and type 1 diabetes mellitus: The most significantly associated haplotype with T1D in AFR and AMR (Table 3) was HLA-DRB1*03:01-DQA1*05:01-DQB1*02:01 (ORAFR = 4.23, PAFR = 1.9 × 10−22; ORAMR = 6.95, PAMR = 2.6 × 10−10).