TNF and neoplasm: After treatment, the drug and microbubble destroyed the microenvironment involved in tumor occurrence, inhibited the enzymes that promote tumor growth and proliferation, blocked the continued growth and metastasis of tumors, and then reduced the production of tumor necrosis factor in the body’s immune response, so that the serum level of tumor body after schisandrine A microbubbles treatment became low (P < 0.01).