LAMA3 and exocrine pancreatic carcinoma: In this study, we integrated data from the TCGA database with four independent datasets from the GEO database as validation cohorts and found that LAMA3 expression was upregulated in PDAC, validating previous study findings.14 Furthermore, through the analysis of clinical samples, we observed that LAMA3 was overexpressed in pancreatic carcinoma tissues compared with adjacent noncancerous tissues.