ESR1 and adenomyosis: Among the various models available to induce adenomyosis, neonatal treatment of CD1 mice with tamoxifen, a selective estrogen receptor modulator, is a model of choice because it appears to reliably produce severe adenomyosis lesions in a high proportion of mice and has been used extensively for examining adenomyosis pathogenesis and drug screening (Green et al. 2005, Yen et al. 2017a, Marquardt et al. 2020).