Histologic examination of IPF lungs has demonstrated the presence of biomarkers associated with senescence in alveolar type 2 (AT2) cells and lung fibroblasts (18), which was confirmed in single cell atlases of IPF lungs showing enrichment of CDKN2A (encoding p16INK4a) expression in epithelial and fibroblast subsets (19, 20). The gene discussed is CDKN2A; the disease is idiopathic pulmonary fibrosis.