The remaining subjects negative for insulinoma had a significantly higher baseline glycaemia, with average 78.53 ± 14.04 mg/dL (range 58–119) (p < 0.001) along with lower insulin (mean 5.15 ± 3.6 μU/mL, p = 0.055) and significantly lower C-peptide (1.51 ± 0.66 ng/mL, p = 0.023). This evidence concerns the gene INS and pancreatic insulinoma.