Furthermore, overexpression of the chemokine CCL2 was sufficient to drive LM in infrequently metastatic medulloblastoma lines ONS76 and MB002, while short hairpin RNA–mediated knockdown of CCL2 in the highly metastatic D425S medulloblastoma line decreased metastasis (Garzia et al., 2018). This evidence concerns the gene CCL2 and medulloblastoma.