The use of AZD9150 could weaken the nucleotide‐biding oligomerization domain containing 1/receptor interacting protein 2 (NOD1/RIP2) signalling pathway which could regulate proinflammatory cytokines IL‐8. In addition IL‐8 are found to stimulate cell proliferation in squamous cell carcinoma of head and neck. The gene discussed is CXCL8; the disease is squamous cell carcinoma.