The use of AZD9150 could weaken the nucleotide‐biding oligomerization domain containing 1/receptor interacting protein 2 (NOD1/RIP2) signalling pathway which could regulate proinflammatory cytokines IL‐8. In addition IL‐8 are found to stimulate cell proliferation in squamous cell carcinoma of head and neck. This evidence concerns the gene RIPK2 and squamous cell carcinoma.