APOE and dementia: The risk of developing AD dementia was significantly impacted by sex, where being male reduced the risk of developing a dementia state by 60%; age, where each additional year increased the risk of dementia by 4%; years of education, where each additional year of education reduced the risk by 17%; and APOE status, where being a carrier of an APOE-ε4 allele increased the risk by 3.41 times.