However, its mutation status in the Chinese population suffering from Brugada Syndrome (BrS) has not been characterized, and the contributory pathophysiological mechanisms to disease pathology remain undefined.<h4>Methods and results</h4>A <i>Scn3b</i> (c.260C>T, p.P87l) mutation was identified in a patient with BrS of Chinese descent. Here, SCN3B is linked to Brugada syndrome.