Consistent with ICG-001-induced differentiation of PBT147 and PBT030 lines, ICG-001 treatment led to a significant reduction in the expression of KIF20A, as measured by qPCR (Figure 1C) (36), further confirming that the differentiating effects of ICG-001 on glioma lines are not cell line dependent. This evidence concerns the gene KIF20A and central nervous system cancer.